In patients who present with large MCA infarcts and are being considered for hemicraniectomy, is there any benefit of early initiation of antiplatelet therapy and DVT prophylaxis?   

Both aspirin and DVT prophylaxis can be started early in patients on hemicraniectomy watch. There is data on increased risk of stroke recurrence in the first 7 days post-stroke and benefits or early initiation of aspirin (even in afib) and decreasing vascular events, especially in the first few week...