Register
Community
Overview
Experts
Editors
Fellows
Code of conduct
Company
About Us
FAQs
Privacy Policy
Terms of Use
Careers
Programs
News
News Releases
Press Coverage
Publications
Blog
Contact Us
Sign in
Please select the option that best describes you:
Topics:
Gastrointestinal Cancers
•
Medical Oncology
•
Liver and Pancreas Tumors
•
Internal Medicine
•
Hepatocellular Carcinoma
•
Gastroenterology
•
Journal Club ft. NEJM publications
•
General Hepatology
Are there any biomarkers that might indicate who might be responders to atezolizumab/bevacizumab for HCC?
ex. VEGFR2 expression, inflammatory signature, PDL1, etc.
Answer from: Medical Oncologist at Academic Institution
Not at this time. Some preliminary studies are being done as ad hoc at this point and was not pre specified before the IMbrave study launching
Comments
Medical Oncologist at University of Texas MD Anderson Cancer Center
Further studies are required for the value of PDL-...
3713
Sign in or Register to read more
Answer from: Medical Oncologist at Community Practice
At this point nothing simple. There was some data presented at AACR 2020 from the single arm study but it looked at signatures. There were interesting findings but not ready for clinical practice
Sign in or Register to read more
8708
8714
Related Questions
How would you manage a solitary unresectable liver metastasis?
How would active Crohn's on Adalimumab affect the adjuvant management of a T2aN0M0 gallbladder cancer?
How long should surgery be delayed in a patient with localized, resectable pancreatic cancer who developed acute pancreatitis following EUS guided biopsy?
In a patient with amyloidosis and abnormal liver function but child Pugh A, would you still proceed with SABR for a liver metastasis?
Would you ever consider using durvalumab/tremelimumab in second line after progression on Atezolizumab and Bevacizumab in advanced HCC?
How would you manage a patient with metastatic HCC on atezolizumab/bevacizumab who requires holding bevacizumab due to persistent proteinuria >2g?
What post-protocol therapies did patients on the BRUIN trial in CLL receive, and how did these therapies impact outcomes?
What approaches can we take to initiate therapy and improve survival rates in patients with HLH?
Would you offer chemoRT to a colon cancer case with a resected polyp with positive margins if the patient wishes to avoid surgery?
What are your first line treatment choices for metastatic combined HCC/Cholangiocarcinoma?
Further studies are required for the value of PDL-...