Are there any subsets of patients where you would consider first-line dacomitinib for EGFR mutations positive NSCLC?

Are there specific mutations or co-mutations were you would consider use of this agent?

Answer from: Medical Oncologist at Community Practice

I continue to favor osimertinib as front line therapy for patients with EGFR mutation positive NSCLC. A retrospective analysis of response and benefit of osimertinib in some less common EGFR mutations was published, including G719X, L861Q, and S768I. The analysis showed clinical benefit with osimert...

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Medical Oncologist at University of Miami Sylvester Comprehensive Cancer Center
I share the same sentiments with @Karen L. Reckamp...

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Are there any subsets of patients where you would consider first-line dacomitinib for EGFR mutations positive NSCLC?

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