General Internal Medicine

Amyloidosis

Questions discussed in this category

Is there any evidence for amyloid/amyloidosis causing a spurious/false PSA reading?

1 Answer available

How do you approach management of a patient with Sjogren's disease and lung mass biopsy revealing amyloidosis?

1 Answer available

How extensive of a workup do you do for systemic AL amyloidosis for a patient with a resected amyloidoma, localized AL amyloid deposition in their airway or lungs, who has no other symptoms?

Would you do a 24-hour urine and echocardiogram in all of these patients? Cardiac biomarkers, PT/PTT, or any other such blood tests?

3 Answers available

Would testing for ATTR cardiac amyloidosis be considered in an older patient with bilateral carpal tunnel surgeries and multiple spinal stenosis surgeries, but no obvious cardiac symptoms?

1 Answer available

What would be your index of suspicion for AL amyloidosis with cardiac involvement in a patient with MGUS to prompt further imaging (and which modality would be preferred)?

1 Answer available

Papers discussed in this category

Blood advances, 2018-05-22

Epidemiology of AL amyloidosis: a real-world study using US claims data.

JACC CardioOncol, 2020 Mar 17

Plasma Hepatocyte Growth Factor for Diagnosis and Prognosis in Light Chain and Transthyretin Cardiac Amyloidosis.

Mayo Clin Proc, 2010 Aug 16

Prevalence of monoclonal gammopathy of undetermined significance: a systematic review.

ESC Heart Fail, 2021 Dec 08

Echocardiographic and clinical predictors of cardiac amyloidosis: limitations of apical sparing.

Haematologica, 2013-01

Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience.

The Lancet. Haematology, 2015 May 06

Natural history and outcomes in localised immunoglobulin light-chain amyloidosis: a long-term observational study.

European respiratory review : an official journal of the European Respiratory Society, 2017 Sep 06

The lung in amyloidosis.

Mayo Clinic proceedings, 2017-06

Presentation and Outcomes of Localized Immunoglobulin Light Chain Amyloidosis: The Mayo Clinic Experience.

Blood Cancer J, 2022 Sep 14

Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: Results of the iStopMM study.

Arthritis Rheumatol, 2021 Jul

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2021 Nov 12

Tissue biopsy for the diagnosis of amyloidosis: experience from some centres.

Radiographics : a review publication of the Radiological Society of North America, Inc, 2013 Nov-Dec

CT findings of thoracic manifestations of primary Sjögren syndrome: radiologic-pathologic correlation.

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