General Internal Medicine

Myeloproliferative Neoplasms

Questions discussed in this category

Is there a role for phlebotomy in secondary polycythemia?

Aside from addressing the underlying case, is there a role for phlebotomy in secondary polycythemia such as in COPD or post-renal transplant erythrocy...

1 Answer available

Is a bone marrow necessary in patient with splenomegaly and polycythemia vera?

1 Answer available

Do you recommend starting an antiplatelet for primary prophylaxis in post splenectomy thrombocytosis given there is some increased risk of venous thrombosis?

If so, what platelet count threshold would you use? Would age impact your decision? Would you do a bone marrow to rule out primary MPD in adults if th...

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Would you consider clearing a patient with essential thrombocytosis for a kidney donation?

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How do you manage and/or prevent ruxolitinib withdrawal syndrome?

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What workup and initial treatment should be considered for suspected autoimmune myelofibrosis?

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How should one manage a patient with leukocytosis and borderline detectable BCR-ABL without other clinical features of CML such as basophilia or splenomegaly?

e.g. IS < 0.002% by qPCR

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In patients with high-risk polycythemia vera with a history of thrombosis, should aspirin be used in addition to indefinite anticoagulation and cytoreduction for prevention of recurrent thrombosis?

What if there are no cardiovascular risk factors? Are VKAs preferred or can DOACs be used?