General Internal Medicine

Spondyloarthritis

Questions discussed in this category

What is your approach to differentiating tender spots (as in fibromyalgia) and enthesitis (as in axSpA)?

How would you approach a patient with axial spondyloarthritis who develops new-onset proteinuria?

How would you manage a patient with highly active ankylosing spondylitis, iritis and Crohn’s, controlled with weekly adalimumab with co-morbid IgG4RD and intolerance of azathioprine due to elevated LFTs?

IgG4 manifestations include autoimmune pancreatitis and periaortic soft tissue mass.

2 Answers available

How do you approach the concept of spondyloarthritis disease activity "burning out" and no longer requiring immunosuppression?

Is there a certain disease duration or age beyond which you taper immunosuppressive treatments?

1 Answer available

How do you typically treat aortitis associated with spondyloarthritis?

1 Answer available

What studies do you find helpful to determine if an axial spondyloarthritis patient presenting late in the disease course with significant irreversible joint damage may benefit from immunosuppression?

1 Answer available

Are there any specific circumstances when you would consider the use of immunosuppression for DISH?

There is some emerging evidence that there is an inflammatory component.

1 Answer available

How do you approach screening for inflammatory bowel disease prior to starting IL-17 inhibitors?

1 Answer available

Do you image the spine in addition to the sacroiliac joints when you suspect axial spondyloarthritis?

Can axSpA affect the spine without affecting the sacroiliac joints?

1 Answer available

What are the benefits of sending HLA B27 genotype over HLA B27 antigen when evaluating for spondyloarthritis?

2 Answers available

How do you differentiate between axial psoriatic arthritis and axial spondylitis with psoriasis, and is it important to distinguish between these two conditions from a prognostic and treatment perspective?

1 Answer available

Papers discussed in this category

Arthritis & rheumatology (Hoboken, N.J.), 2016-05

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis.

Arthritis Rheumatol, 2019 Oct

2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis.

Rheumatology (Oxford),

Is axial psoriatic arthritis distinct from ankylosing spondylitis with and without concomitant psoriasis?

Rheumatology (Oxford),

Axial disease in psoriatic arthritis.

Clin. Exp. Rheumatol., 2016 Dec 13

Clinical and genetic associations of radiographic sacroiliitis and its different patterns in psoriatic arthritis.

Lancet, 2015 Oct 01

Effect of tight control of inflammation in early psoriatic arthritis (TICOPA): a UK multicentre, open-label, randomised controlled trial.

J Rheumatol Suppl,

GRAPPA 2018 Project Report.

Nat Rev Rheumatol,

Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison.

Rheumatology (Oxford),

Treatment guidelines in psoriatic arthritis.

Ann Rheum Dis, 2015 Dec 07

European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update.

Curr Rheumatol Rep,

Polymorphism of HLA-B27: 105 subtypes currently known.

Ann Rheum Dis, 2011 Jul 28

HLA-B27 positive patients differ from HLA-B27 negative patients in clinical presentation and imaging: results from the DESIR cohort of patients with recent onset axial spondyloarthritis.

Ann Rheum Dis, 2014 Jan 22

Does spinal MRI add incremental diagnostic value to MRI of the sacroiliac joints alone in patients with non-radiographic axial spondyloarthritis?

Ann Rheum Dis, 2012 May 14

Descriptions of spinal MRI lesions and definition of a positive MRI of the spine in axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI study group.

Ann Rheum Dis, 2015 Aug 18

Patients with chronic back pain of short duration from the SPACE cohort: which MRI structural lesions in the sacroiliac joints and inflammatory and structural lesions in the spine are most specific for axial spondyloarthritis?

Arthritis Rheumatol, 2020 May

Effect of Therapy on Radiographic Progression in Axial Spondyloarthritis: A Systematic Review and Meta-Analysis.

Gut, 1999-04

Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses.

Gut, 2012-12

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial.

Annals of the rheumatic diseases, 2019-04

Incidence rates of inflammatory bowel disease in patients with psoriasis, psoriatic arthritis and ankylosing spondylitis treated with secukinumab: a retrospective analysis of pooled data from 21 clinical trials.

Ann Rheum Dis, 2014 Mar 21

The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study.

Current rheumatology reports, 2009-10

Diffuse idiopathic skeletal hyperostosis: differentiation from ankylosing spondylitis.

Radiology,

Radiographic and pathologic features of spinal involvement in diffuse idiopathic skeletal hyperostosis (DISH).

Curr Rheumatol Rep, 2021 Jan 26

Diffuse Idiopathic Skeletal Hyperostosis (DISH) and a Possible Inflammatory Component.

RMD Open, 2019

Predictors of remission in patients with non-radiographic axial spondyloarthritis receiving open-label adalimumab in the ABILITY-3 study.

Best practice & research. Clinical rheumatology, 2014 Nov 10

Spontaneous, drug-induced, and drug-free remission in peripheral and axial spondyloarthritis.

Rheumatology (Oxford, England), 2022 Apr 11

Factors associated with remission at 5-year follow-up in recent-onset axial spondyloarthritis: results from the DESIR cohort.

General Internal Medicine

Spondyloarthritis

Questions discussed in this category

Papers discussed in this category

Related Topics in General Internal Medicine