Systemic autoimmune diseases   

Do you have thoughts in general about the potential of TYK2 inhibition for these difficult to treat diseases?This question is part of a collaboration ...

This question is part of a collaboration with RheumMadness and is specifically in reference to: Cost Effectiveness of HCQ Screening.

This question is part of a collaboration with RheumMadness and is specifically in reference to: Long-term outcomes of anifrolumab in SLE.

When do you switch to steroid-sparing medications? What steroid-sparing therapies do you prefer?

Do you do blood work? Or do you rely on review of systems?

Do you typically start the patient on hydroxychloroquine?  What work-up do you perform?

In what cases do you discontinue the medication?

What recommendations do you provide if there is concern that the patient is beginning to flare? Have you prescribed any of the new JAK inhibitors?