Hospital Medicine

HIV & AIDS

Questions discussed in this category

What is your approach when cryptococcus serum or CSF antigen titers do not change despite treatment in HIV-positive patients with cryptococcal meningitis or invasive disease, but there is clinical improvement and cultures remain negative?

1 Answer available

In clinical practice, are you using single-dose liposomal amphotericin B for treatment of cryptococcal meningitis for patients living with HIV?

1 Answer available

What is your approach to starting antiretroviral therapy in a patient living with HIV who is diagnosed with cryptococcal meningitis?

1 Answer available

Do you treat patients with HIV-AIDS and positive cryptococcal antigenemia but negative CSF cryptococcal antigen with standard meningitis treatment given the potential for the postzone effect?

1 Answer available

Do you rule out TB in patients with AIDS and lobar pneumonia?

What’s your threshold to get the three AFBs and place the patient in airborne isolation?

1 Answer available

Papers discussed in this category

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019-01-18

Short-course High-dose Liposomal Amphotericin B for Human Immunodeficiency Virus-associated Cryptococcal Meningitis: A Phase 2 Randomized Controlled Trial.

The New England journal of medicine, 2022 Mar 24

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.

The Cochrane database of systematic reviews, 2018 Jul 24

Early versus delayed antiretroviral treatment in HIV-positive people with cryptococcal meningitis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023 Jul 05

Early Antiretroviral Therapy Not Associated With Higher Cryptococcal Meningitis Mortality in People With Human Immunodeficiency Virus in High-Income Countries: An International Collaborative Cohort Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994-05

Measurement of cryptococcal antigen in serum and cerebrospinal fluid: value in the management of AIDS-associated cryptococcal meningitis.

HIV clinical trials, 2000

Clinical utility of monitoring serum cryptococcal antigen (sCRAG) titers in patients with AIDS-related cryptococcal disease.

Journal of clinical microbiology, 2005 Nov

The role of cryptococcal antigen assay in diagnosis and monitoring of cryptococcal meningitis.

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