Hospital Medicine

Neuro-critical care   

Questions discussed in this category



Considering the short half-life, at what point would it be deemed too late to administer any reversal agent, and to consider withholding it?

Have recent trials (TRAIN trial and HEMOTION trial) influenced your approach? 

Blood pressure targets for ischemic stroke and intracerebral hemorrhage are described in several guidelines. However, in patients with acute stroke wh...

In the span between the HACA trial and the Targeted Temperature Management in Out-of-Hospital Cardiac Arrest study (Dankiewicz et al., PMID 34133859),...

Plasmapheresis first or IVIG first in GBS? What other treatment options are there for severe disabling GBS?

Given the risk of elevated ICP, would you attempt a brain MRI to further characterize the lesion? Or would CT imaging suffice prior to intervention?

For patients who are unable to have complete brain stem testing, would you recommend apnea testing prior to ancillary tests in case of suspected brain...

For instance, if the patient doesn’t tolerate apnea testing, is too unstable to go for ancillary testing outside the ICU, and TCDs/EEG are unava...

Is there any benefit to starting hyperosmolar therapy prior to the development of depressed level of consciousness or midline shift?


Papers discussed in this category


Neurotherapeutics,

Lancet Neurol, 2017 Sep

The Lancet. Neurology, 2016-05

JAMA,

The New England journal of medicine, 2002-02-21

N Engl J Med, 2013 Nov 17

Cureus, 2022 Sep 11

Crit Care, 2020 Jan 06

The Lancet. Neurology, 2007 Mar

Stroke, 2022 May 17

Neurology, 2020 Sep 01

Lancet Neurol, 2021 Mar 17

Neurocritical care, 2005

Clinical neurophysiology practice, 2022 May 16

Neurocritical care, 2023 Nov 03

JAMA, 2022 May 17

JAMA, 2013 May 22