Internal Medicine

COVID-19

Questions discussed in this category

What is your preferred first-line treatment for chronic fatigue in patients with long COVID-19?

7 Answers available

Do you consider the use of tocilizumab in patients with COVID pneumonia who have had an improvement in supplemental O2 requirements but have significantly elevated inflammatory markers after day two of remdesivir and dexamethasone?

1 Answer available

Do you consider use of convalescent plasma early in disease course in COVID-19 induced ARDS in mechanically ventilated patients?

Do the results of the recent study (Misset et al., PMID 37889107) showing reduction in 28-day mortality in patients with high neutralizing antibody ti...

1 Answer available

What is your approach to the use of Paxlovid for patients with risk factors for severe Covid-19 infection but who have received SARS-CoV-2 vaccines in light of the EPIC-SR trial findings?

EPIC-SR Trial

2 Answers available

Do you use steroids in patients with respiratory failure who are infected with both influenza and COVID-19?

How do you approach which risk to accept given that steroids have evidence for use in COVID-19 while is suggestion for harm in using steroids in influ...

1 Answer available

Do you use prednisone in the management of patients with persistent respiratory symptoms following acute COVID-19 infection?

4 Answers available

Is rituximab for refractory ITP contraindicated in the setting of an active COVID infection, particularly in a patient with asymptomatic COVID?

2 Answers available

What steroid regimen do you employ in the treatment of patients with post COVID-19 pulmonary fibrosis?

2 Answers available

In a patient with a bleeding disorder, how would one approach anticoagulation during active COVID infection?

Bleeding disorder such as vWD

1 Answer available

Is there a role for antifibrotic therapy in post COVID-19 pulmonary fibrosis?

1 Answer available

Do you recommend routine use of Evusheld for pre-exposure prophylaxis for patients on immunosuppression?

Does treatment with B-cell depletion and/or negative anti-spike antibody status despite COVID mRNA vaccination influence your decision?

1 Answer available

How have you been counseling patients with sickle cell regarding a 3rd COVID vaccine?

3 Answers available

Should we recommend the COVID-19 booster vaccine to patients who had a DVT or any other complications such as hemolytic anemia or thrombocytopenia from prior vaccine doses?

2 Answers available

In a patient with a heterozygous prothrombin gene mutation who has COVID with minimal symptoms, do you recommend prophylactic and/or therapeutic anticoagulation?

1 Answer available

Are there any alternative, hypofractionated RT courses for patients with DLBCL that can be used during the COVID-19 pandemic?

2 Answers available

Do you routinely check platelet counts after COVID-19 vaccines in patients with chronic ITP?

1 Answer available

Is there a role for antibody testing to confirm vaccine response for patients on rituximab after COVID-19 vaccination?

1 Answer available

Do you recommend COVID vaccination in patients with antiphospholipid antibody positivity or other prothrombotic states not on anti-coagulation?

1 Answer available

What hematologic conditions are contraindications for a COVID vaccine?

2 Answers available

How are you timing the third dose of the COVID-19 mRNA vaccine in patients on rituximab?

1 Answer available

In which patients with autoimmune or inflammatory conditions are you recommending a 3rd dose of the mRNA COVID vaccine?

2 Answers available

How do you advise a patient with VTE on indefinite anticoagulants regarding the Ad26.COV2.S Johnson & Johnson/Janssen COVID vaccine?

1 Answer available

How would you advise patients with known stable autoimmune thrombocytopenia regarding the Ad26.COV2.S (Johnson & Johnson/Janssen) vaccine?

1 Answer available

How do you advise patients who had autoimmune diseases "triggered" by COVID infections on getting COVID vaccination?

E.g., inflammatory polyarthritis or inflammatory myopathy with onset within 2 weeks of documented COVID infection

1 Answer available

What are the current official guidelines regarding COVID-19 vaccination for patients with cancer or for hematologic conditions?

2 Answers available

Are there particular concerns related to the use of B-cell depletion therapies such as rituximab for rheumatic disease during the COVID-19 pandemic?

1 Answer available

How would you time COVID-19 vaccination with someone on R-CHOP chemotherapy?

1 Answer available

Are you recommending the mRNA COVID-19 vaccines to your patients with immune mediated inflammatory diseases?

5 Answers available

Do you recommend that children with sickle cell disease refrain from returning to school during the COVID-19 pandemic?

2 Answers available

Is there an increased risk of pneumonitis in COVID-19+ patients receiving lung irradiation?

Any differences in the risks between SBRT vs. conventionally fractionation? Concurrent immunotherapy?

1 Answer available

Would you stop current immunosuppressive therapy or delay starting immunosuppressive therapy in a patient with aplastic anemia who has been infected with COVID-19?

2 Answers available

Would you recommend anticoagulation prophylaxis for a pediatric patient admitted with COVID-19?

3 Answers available

Are patients with bleeding disorders receiving plasma-derived products at increased risk of acquiring COVID-19?

1 Answer available

Should patients with bleeding disorders increase their home supplies of clotting factors foreseeing a possible shortage of product availability due to COVID-19?

1 Answer available

How would you manage a patient with sickle cell disease who is infected with COVID-19?

1 Answer available

How has COVID-19 altered your recommendations for invasive mediastinal staging for NSCLC?

Should staging and treatment decisions be made based on imaging alone?

2 Answers available

Papers discussed in this category

Adv Radiat Oncol, 2020 May 05

Need for Caution in the Diagnosis of Radiation Pneumonitis in the COVID-19 Pandemic.

Cancer Discov, 2020 May 01

Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System.

Lancet, 2020 May 28

Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.

Int. J. Radiat. Oncol. Biol. Phys., 2020 Apr 14

Practice Recommendations for Risk-Adapted Head and Neck Cancer Radiation Therapy During the COVID-19 Pandemic: An ASTRO-ESTRO Consensus Statement.

Acta Paediatr., 2020 Mar 23

Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults.

Rheumatol Int, 2020 Sep 18

High rates of severe disease and death due to SARS-CoV-2 infection in rheumatic disease patients treated with rituximab: a descriptive study.

Lancet Rheumatol, 2021 Apr 06

Incident systemic rheumatic disease following COVID-19.

N Engl J Med, 2020 Nov 20

Covid-19-Associated Myopathy Caused by Type I Interferonopathy.

Blood,

Adenovirus-induced thrombocytopenia: the role of von Willebrand factor and P-selectin in mediating accelerated platelet clearance.

N Engl J Med, 2021 Apr 14

Thrombotic Thrombocytopenia after Ad26.COV2.S Vaccination.

Arthritis Rheumatol, 2021 May 24

American College of Rheumatology Guidance for COVID-19 Vaccination in Patients With Rheumatic and Musculoskeletal Diseases: Version 1.

Semin Hematol,

Epidemiology and risk factors for venous thrombosis.

Am J Hematol, 2021 Jun 29

BNT162b2 COVID-19 vaccine is significantly less effective in patients with hematologic malignancies.

Blood, 2010-11-04

Severe pandemic H1N1 and seasonal influenza in children and young adults with sickle cell disease.

Pediatric blood & cancer, 2014-05

Respiratory syncytial virus and seasonal influenza cause similar illnesses in children with sickle cell disease.

British journal of haematology, 2015-05

Immune parameter analysis of children with sickle cell disease on hydroxycarbamide or chronic transfusion therapy.

Oman Med J, 2020 Nov 07

Respiratory Viral Infections in Sickle Cell Anemia: Special Emphasis on H1N1 Co-infection.

Pediatr Blood Cancer, 2020 Sep 08

Fatal viral infections in hemoglobin sickle cell C patients.

Blood Adv,

COVID-19 in individuals with sickle cell disease/trait compared with other Black individuals.

Hemoglobin, 2021 May 24

Incidence Rate of COVID-19 Infection in Hemoglobinopathies: A Systematic Review and Meta-analysis.

Thromb Res, 2021 Jun 25

Absence of hypercoagulability after nCoV-19 vaccination: An observational pilot study.

Eur Respir Rev, 2021 Dec 15

Recovering from a pandemic: pulmonary fibrosis after SARS-CoV-2 infection.

Ann Am Thorac Soc,

Persistent Post-COVID-19 Interstitial Lung Disease. An Observational Study of Corticosteroid Treatment.

Medical sciences (Basel, Switzerland), 2018-09-21

Low-Dose Naltrexone (LDN)-Review of Therapeutic Utilization.

The Journal of clinical investigation, 2021 Dec 15

The intersection of COVID-19 and autoimmunity.

Molecular systems biology, 2023 Mar 15

A methylation clock model of mild SARS-CoV-2 infection provides insight into immune dysregulation.

BMJ open, 2024 May 13

Low-dose naltrexone for post-COVID fatigue syndrome: a study protocol for a double-blind, randomised trial in British Columbia.

N Engl J Med, 2012 May 20

Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis.

The New England journal of medicine, 2024 Apr 04

Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with Covid-19.

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