Internal Medicine

Vaccines   

Questions discussed in this category



Is there a role for booster vaccination and if so, how do you approach the timing when a patient is already on a biologic for immunosuppression? 

E.g., for a patient with myeloma, s/p induction therapy, and high-dose chemotherapy, followed by autologous rescue with inappropriate antibody respons...

For example, in patients who are HbSAg negative, anti-HBc positive and HbSAb negative, does vaccination reduce reactivation risk?

If a deficiency is present, do you consider IVIG to treat non-infectious symptoms such as skin rash, arthritis or hematological abnormalities? 

E.g., inflammatory polyarthritis or inflammatory myopathy with onset within 2 weeks of documented COVID infection


Papers discussed in this category


Lancet Rheumatol, 2021 Apr 06

N Engl J Med, 2020 Nov 20

Blood,

Arthritis Rheumatol, 2021 May 24

Semin Hematol,

Thromb Res, 2021 Jun 25

Semin Arthritis Rheum, 2007 Feb

J Clin Rheumatol, 2021 Dec 01

Am J Med, 1984 Mar 30

Lupus, 2007

Autoimmun Rev, 2022 Aug 24

Lupus, 2014 Jul 30

MMWR. Morbidity and mortality weekly report, 2024 Sep 12