Pediatric Hematology/Oncology

Gynecologic Oncology

Questions discussed in this category

What special considerations do you take when treating cancer patients with severe intellectual disabilities?

Have you been able to deliver standard of care treatment?

1 Answer available

Is there evidence to support or argue against intermittent fasting for cancer patients?

3 Answers available

How can oncologists be more collaborative with palliative care physicians?

How can these interactions be improved?

1 Answer available

How do you clearly communicate to parents that the main purpose of a phase I trial is to find the best dose of a new drug with the fewest side effects rather than treating the patient's cancer?

There is evidence that parents do not adequately understand the purpose of phase I pediatric cancer trials (Cousino et al., PMID 23071225).

1 Answer available

How do you discern whether elevated liver enzymes are from immunotherapy versus chemotherapy when a patient is on combination chemo/immunotherapy?

2 Answers available

When do you refer patients for germline testing when somatic tumor testing is negative for actionable mutations?

How reliable is somatic testing to detect an underlying germline predisposition?

2 Answers available

Papers discussed in this category

Gastroenterology, 1993-06

Hepatoprotective properties of ursodeoxycholic acid.

Gastroenterology, 1991 Jul

Evidence for a direct hepatoprotective action of ursodeoxycholic acid in primary human hepatocytes.

Z Naturforsch C J Biosci, 2002 Mar-Apr

Prophylactic effect of aqueous propolis extract against acute experimental hepatotoxicity in vivo.

Immunopharmacol Immunotoxicol, 2003 Nov

Hepatoprotective effect of baicalin, a major flavone from Scutellaria radix, on acetaminophen-induced liver injury in mice.

Exp Toxicol Pathol, 2002 Feb

Acetaminophen hepatotoxicity and mechanisms of its protection by N-acetylcysteine: a study of Hep3B cells.

Biochem Biophys Res Commun, 1999 Sep 24

Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants.

Ital J Gastroenterol Hepatol, 1998 Dec

Amantadine hydrochloride decreases serum ALT activity without effects on serum HCV-RNA in chronic hepatitis C patients.

Chem Biol Interact, 2001 Dec 21

Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents.

Journal of palliative medicine, 2012-11

Conceptual models for integrating palliative care at cancer centers.

Nature reviews. Clinical oncology, 2016-03

Integrating palliative care into the trajectory of cancer care.

JAMA Oncol,

Prolonged Nightly Fasting and Breast Cancer Prognosis.

Aging, 2009-12-31

Fasting and cancer treatment in humans: A case series report.

Cell cycle (Georgetown, Tex.), 2010-11-15

Fasting and differential chemotherapy protection in patients.

BMC cancer, 2016-06-10

Safety and feasibility of fasting in combination with platinum-based chemotherapy.

BMC Cancer, 2015 Oct 05

The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study.

BMC Cancer, 2018 Apr 27

The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study.

Int J Radiat Oncol Biol Phys, 2020 Jun 30

ERGO2: A Prospective, Randomized Trial of Calorie-Restricted Ketogenic Diet and Fasting in Addition to Reirradiation for Malignant Glioma.

Contemporary clinical trials, 2017-02

DIETFITS study (diet intervention examining the factors interacting with treatment success) - Study design and methods.

Pediatric Hematology/Oncology

Gynecologic Oncology

Questions discussed in this category

Papers discussed in this category

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