Primary Care

Neuro-immunology

Questions discussed in this category

Should IVIG dosing in patients with autoimmune disease (i.e., dermatomyositis) who become pregnant continue to be based on actual weight at the time of each infusion, or should it be limited to pre-pregnancy weight?

2 Answers available

How do you approach managing nausea and GI side effects when initiating methotrexate?

5 Answers available

In a patient with neurosarcoidosis who required infliximab for initially refractory symptoms but is now stable, how do you decide on the optimal time to de-escalate therapy?

1 Answer available

Do you discontinue or adjust azathioprine when a patient develops elevated MCV after starting it?

When it seems fairly certain that this is a drug effect is it something that can just be monitored or requires a change in approach?

2 Answers available

Papers discussed in this category

Neurology, 2017-11-14

Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series.

Neurol Neuroimmunol Neuroinflamm, 2020 Jul 27

Infliximab treatment in pathology-confirmed neurosarcoidosis.

Medicine, 2021 Jan 08

Prospective, double-blind, randomized, placebo-controlled phase III study evaluating efficacy and safety of octagam 10% in patients with dermatomyositis ("ProDERM Study").

Curr Rheumatol Rep, 2023 Aug

Intravenous Immunoglobulin in Idiopathic Inflammatory Myopathies: a Practical Guide for Clinical Use.

NeoReviews, 2021 Jan

Update on the Use of Intravenous Immunoglobulin in Pregnancy.

Journal of clinical pharmacology, 2023 Jun

Physiologic Changes During Pregnancy and Impact on Small-Molecule Drugs, Biologic (Monoclonal Antibody) Disposition, and Response.

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