Primary Care

UCLA

Questions discussed in this category

Is there evidence that oral contraceptive pills are less effective in pre-menopausal women on tamoxifen chemoprevention?

We usually recommend copper IUDs, but that's not feasible in all women.

1 Answer available

Would you consider HRT after BSO in a pre-menopausal gBRCA2+ patient who has no intention of ever having prophylactic bilateral mastectomies and who declines chemoprophylaxis?

2 Answers available

How do you advise women who are at high risk for breast cancer and for whom annual screening breast MRIs are recommended regarding the long-term risks of gadolinium contrast?

1 Answer available

Would you consider giving tamoxifen prophylaxis to young women with pathogenic BRCA2 muations who are <35 years old?

Tamoxifen prophylaxis has not been studied in women <35 years old, but it would be reasonable to assume they would benefit.

1 Answer available

For patients at high risk of breast cancer, do you recommend tomosynthesis over traditional two-view screening mammogram?

1 Answer available

How do you counsel a patient with a history of breast cancer regarding use of breast MRI for screening?

Patient does not qualify for breast cancer screening by annual MRI per criteria (IBIS lifetime risk<20%, no known genetic predisposition,...

1 Answer available

Papers discussed in this category

Lancet Oncol., 2016 Jun 23

Breast cancer screening with tomosynthesis (3D mammography) with acquired or synthetic 2D mammography compared with 2D mammography alone (STORM-2): a population-based prospective study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-09-01

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004-06-15

Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.

J. Natl. Cancer Inst.,

Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial.

Obstet Gynecol,

Long-term mortality associated with oophorectomy compared with ovarian conservation in the nurses' health study.

JAMA,

Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-term Follow-up of the Women's Health Initiative Randomized Clinical Trials.

Cancer Prev Res (Phila), 2019 Aug 16

Effect of Bazedoxifene and Conjugated Estrogen (Duavee) on Breast Cancer Risk Biomarkers in High-Risk Women: A Pilot Study.

Related Topics in Primary Care