Rheumatology

Pregnancy

Questions discussed in this category

In a patient with SJIA who has been stable on Anakinra however is now planning to conceive or becomes pregnant, would you consider switching to Cimzia?

1 Answer available

What is your approach to transitioning an SLE patient from a pregnancy incompatible regimen to pregnancy compatible regimen?

For example, when switching from MMF to azathioprine, do you overlap the treatments as you lower the dose of one and add the other?

3 Answers available

Would you use belimumab in a breastfeeding patient with SLE who has persistent joint pain, leukopenia and elevated dsDNA despite HCQ and azathioprine?

3 Answers available

Do you continue belimumab throughout pregnancy?

4 Answers available

Is there a concern for the potential of future congenital malformations in offspring when preservation of eggs and sperm is done AFTER cyclophosphamide treatment given that it is an alkylating agent?

1 Answer available

Do you stop TNF inhibitors during the third trimester of pregnancy?

2 Answers available

How would you manage tubulointerstitial nephritis and renal tubular acidosis (RTA) in a patient with Sjogren's who is pregnant?

2 Answers available

What would be your approach to a SLE patient who is triple APS positive, has no prior VTE/obstetric events, is stable on HCQ and low dose aspirin, and wants to become pregnant?

2 Answers available

How do you counsel patients regarding contraception use while taking mycophenolate/mycophenolic acid?

2 Answers available

How do you assess potential fetal harm in patients who have unplanned pregnancy while taking teratogenic medications?

1 Answer available

How do you monitor a patient with scleroderma during pregnancy?

1 Answer available

Do you ever consider treatment outside of the peripartum period in a patient with a history of obstetric APS?

i.e. obstretric APS without thrombosis or SLE

2 Answers available

What is your approach to differentiating SLE flare in pregnancy vs pre-eclampsia?

1 Answer available

Does serologic activity (e.g., high titer dsDNA, low complements) without clinical disease activity in a pregnant lupus patient affect maternal or fetal outcomes?

2 Answers available

Papers discussed in this category

Current rheumatology reports, 2018-09-10

Primary Thrombosis Prophylaxis in Persistently Antiphospholipid Antibody-Positive Individuals: Where Do We Stand in 2018?

Nat Rev Cardiol, 2019 Jun 26

Role of aspirin in primary prevention of cardiovascular disease.

Ann Rheum Dis, 2016 Feb 17

The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation.

Arthritis Rheumatol, 2020 Apr

2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.

Rheumatology (Oxford), 2022 Nov 02

British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids.

Rheumatic diseases clinics of North America, 2021 Feb 25

The Categorization of Pain in Systemic Lupus Erythematosus.

Lupus science & medicine, 2023 Jan

Molecular endotypes of type 1 and type 2 SLE.

Nat Rev Nephrol, 2015 Nov 16

Renal involvement in primary Sjögren syndrome.

Ann Rheum Dis, 2022 Oct 05

Belimumab use during pregnancy: a summary of birth defects and pregnancy loss from belimumab clinical trials, a pregnancy registry and postmarketing reports.

Ann Rheum Dis, 2023 Jan 05

Transplacental passage of belimumab during pregnancy and follow-up of a child exposed in utero.

Lupus, 2022 Nov 30

Dilemma of belimumab therapy (dis)continuation during pregnancy: Results of a retrospective study in eudravigilance.

Current opinion in rheumatology, 2014-03

Systemic lupus erythematosus and pregnancy outcomes: an update and review of the literature.

Rheumatology (Oxford, England), 2013 Feb 04

Low risk of renal flares and negative outcomes in women with lupus nephritis conceiving after switching from mycophenolate mofetil to azathioprine.

Journal of clinical medicine, 2021 Dec 31

A Systematic Review of the Safety of Blocking the IL-1 System in Human Pregnancy.

Rheumatology

Pregnancy

Questions discussed in this category

Papers discussed in this category

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