Allergy & Immunology

Gastroenterology

Questions discussed in this category

When do you consider de-escalating therapy such as dupilumab in eosinophilic esophagitis?

Would you consider anti-IL-5 therapy (mepolizumab or benralizumab) to either prevent or treat the more severe manifestations of eosinophilic granulomatosis with polyangiitis, such as "infiltrative" (e.g., cardiomyopathy, pulmonary infiltrates, or gastroenteritis) or "vasculitic" (e.g., neuropathy, palpable purpura, or glomerulonephritis)?

2 Answers available

In a young patient who was vaccinated to chickenpox as a child (no previous varicella infection) should the patient receive a shingles vaccine prior to starting Rinvoq?

Specifically for a male in his 20s.

3 Answers available

How would you approach diagnosis of a patient with recurrent episodes of abdominal pain, severe myalgias, low grade fevers and urticaria?

Does this presentation fall within the autoinflammatory spectrum, and is it consistent with FMF or would you consider another cytokine-driven process?...

5 Answers available

In light of recent measles outbreaks in the US, would you recommend an MMR booster for an immunocompetent patients born before 1957?

6 Answers available

What therapies would be considered safe and effective in pregnant patients with EoE?

2 Answers available

Is there a role for use of dupilumab for hypereosinophilic GI disorders distal to the esophagus?

2 Answers available

Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?

1 Answer available

Is there a role for anti-IL5 therapy in the treatment of EoE?

1 Answer available

Do you recommend food elimination diets for GI eosinophilic disorder not affecting the esophagus?

1 Answer available

What is your approach to working up diarrhea in an immunocompromised patient?

1 Answer available

Papers discussed in this category

The Journal of allergy and clinical immunology, 2023 Jul 18

Prospective study of an amino acid-based elemental diet in an eosinophilic gastritis and gastroenteritis nutrition trial.

The Journal of allergy and clinical immunology, 2012-02

Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial.

Gut, 2023 Jul 09

Mepolizumab for treatment of adolescents and adults with eosinophilic oesophagitis: a multicentre, randomised, double-blind, placebo-controlled clinical trial.

The New England journal of medicine, 2024 Jun 27

Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis.

The Journal of infection, 2011-11

Norovirus gastroenteritis successfully treated with nitazoxanide.

Alimentary pharmacology & therapeutics, 2006 Nov 15

Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.

Journal of tropical medicine, 2017 Feb 26

Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country.

Annals of internal medicine, 2025 Jul 29

Rituximab Versus Conventional Therapy for Remission Induction in Eosinophilic Granulomatosis With Polyangiitis : A Randomized Controlled Trial.

Allergy & Immunology

Gastroenterology

Questions discussed in this category

Papers discussed in this category

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