Internal Medicine

Thalassemia

Questions discussed in this category

How quickly do you expect iron stores to decrease after starting iron chelators?

After what time period would you consider adding a second iron chelator?

1 Answer available

How do you optimize a beta thalassemia patient on luspatercept who is interested in becoming pregnant?

When do you stop luspatercept? How do you approach iron chelation therapy if the patient is currently on therapy?

1 Answer available

How do you manage arthritis resulting from deferiprone in transfusion dependent thalassemia?

1 Answer available

What hemoglobin level do you target for adult beta thalassemia intermedia patients with a pre-transfusion Hb >7 g/dl?

Should adult hemoglobin targets be different than pediatrics?

1 Answer available

What is your strategy for optimizing hydroxyurea dosage in patients with symptomatic sickle cell disease, particularly for genotypes HbSS and HbS/Beta thal?

1 Answer available

Papers discussed in this category

The New England journal of medicine, 2008-03-27

Hydroxyurea for the treatment of sickle cell anemia.

The New England journal of medicine, 2020 Jun 25

Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa.

Frontiers in genetics, 2022 Aug 26

Barriers to hydroxyurea use from the perspectives of providers, individuals with sickle cell disease, and families: Report from a U.S. regional collaborative.

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