ITP   

Questions discussed in this category


Is the thrombotic risk associated with TPO-RAs only relevant to VTE or does it also apply to arterial thromboses and stroke? Can the risk be mitigated...

Initial labs obtained? Factors to consider when deciding admission vs outpatient management? Threshold for treatment? Treatment with steroids vs ...

What if there is continued thrombocytopenia despite reaching complete remission (with incomplete marrow recovery)?

Received dexamethasone 40 mg daily x4 and IVIG without response. No DIC. PB flow cytometry and bone marrow biopsy without pathology. Are there specifi...

Such as the case in which a patient is unresponsive to steroids, IVIG, TPO-agonist, rituximab, splenectomy, and even fostamitinib.

For example, do we prefer one regimen over the other in patients with a bleeding history or who have relapsed after a lengthy remission?

Would you consider high-dose dexamethasone (deliberating adverse effects of antenatal steroids) or move to next-line therapies?


Papers discussed in this category


The New England journal of medicine, 2013-02-21

The New England journal of medicine, 2017 Mar 18

British journal of haematology, 2019-05

Blood Adv, 2019 Dec 10