Medical Oncology

Genetic Liver Disease

Questions discussed in this category

What parameters would you use to monitor and interpret iron levels in a hemochromatosis patient where ferritin is unreliable due to underlying chronic inflammation?

How would your recommendation change if the patient has H63 homozygous mutation?

2 Answers available

Under which circumstances would you prefer ropeginterferon over hydroxyurea for patients with Polycythemia Vera?

Ropeginterferon is now a preferred therapy for Polycythemia Vera (PV) as per a recent update to the NCCN guidelines.

1 Answer available

What is the indication for phlebotomy in compound heterozygous hemochromatosis?

What is the ferritin target that you would aim for? What would be your approach for a ferritin >500? When do you order an MRI liver for iron quanti...

1 Answer available

Papers discussed in this category

Blood, 2010-04-08

Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms.

Blood, 2008-07-15

The revised World Health Organization diagnostic criteria for polycythemia vera, essential thrombocytosis, and primary myelofibrosis: an alternative proposal.

Seminars in hematology, 1986-04

Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols.

N Engl J Med, 2014 Aug 28

Two clinical phenotypes in polycythemia vera.

Leukemia, 2021 Apr 28

Are polycythemia vera, essential thrombocytosis, and primary myelofibrosis 1, 2, or 3 diseases?

Blood, 2022 May 12

A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia.

Haematologica, 2019 Apr 04

Distinguishing essential thrombocythemia V617F from polycythemia vera: limitations of erythrocyte values.

Blood, 1997 Nov 01

Treatment of polycythemia vera: the use of hydroxyurea and pipobroman in 292 patients under the age of 65 years.

Blood, 2023 Nov 30

Moving toward disease modification in polycythemia vera.

Blood, 2008 Jan 10

A dynamic prognostic model to predict survival in post-polycythemia vera myelofibrosis.

Lancet (London, England), 1978 Dec 09

Vascular occlusive episodes and venous haematocrit in primary proliferative polycythaemia.

Medical Oncology

Genetic Liver Disease

Questions discussed in this category

Papers discussed in this category

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