Ocular Oncology

Questions discussed in this category

What is your approach for LINAC based radiosurgery when dealing with benign perioptic lesions very close to the optics apparatus?

For LINAC radiosurgery systems, when would you neither offer hypofractionated SRS or SRS for benign perioptic lesions? Is there a distance from the op...

1 Answer available

What dose would you use for a plaque brachytherapy for a melanoma involving the iris?

1 Answer available

How would you approach a patient with vitreoretinal lymphoma without CNS or systemic involvement?

What would be your RT volumes and dose?

2 Answers available

What screening recommendations do you provide for patients with a Nevus of Ota with ocular involvement?

2 Answers available

Would you consider SBRT for an intraocular/choroidal metastasis?

If so, what dose/fractionation and constraints would you recommend?

2 Answers available

Is there a role for radiation therapy in the treatment of a lymphoproliferative disorder involving the orbit?

If so, what dose and fractionation would you recommend?

4 Answers available

What would you recommend for a patient with bilateral conjunctival MALT (without systemic disease)?

In this scenario, is systemic treatment better given bilateral involvement? In a patient who has already had cataract surgery and is not at risk for c...

1 Answer available

Should regular screening brain MRIs be done for children with germline RB1 mutation in addition to eye exams?

Would you recommend screening MRIs for children who have RB1 mutations but have not yet developed retinoblastoma?

1 Answer available

When should proton beam therapy be considered for uveal melanoma?

Are there exclusion criteria?

3 Answers available

How do you account for tumor growth from pre-operative to intra-operative ultrasound for uveal melanoma?

Do you prescribe to 5mm/apex or use a margin? Do you add time for tumor growth or allow less than the prescription dose to the apex?

2 Answers available

When is postoperative radiation indicated after enucleation of an ocular melanoma?

Is extrascleral extension or optic nerve invasion an indication? I can find little in the literature or textbooks discussing this issue, likely ...

1 Answer available

What should be the first line treatment for metastatic uveal melanoma?

1 Answer available

Papers discussed in this category

Ophthalmology, 2002-10

Late radiation failures after iodine 125 brachytherapy for uveal melanoma compared with charged-particle (proton or helium ion) therapy.

Archives of ophthalmology (Chicago, Ill. : 1960), 2002-12

Evidence-based estimates of outcome in patients irradiated for intraocular melanoma.

Am. J. Ophthalmol.,

The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre-enucleation radiation of large choroidal melanoma: IV. Ten-year mortality findings and prognostic factors. COMS report number 24.

International journal of radiation oncology, biology, physics, 2001-03-15

Proton radiation therapy for medium and large choroidal melanoma: preservation of the eye and its functionality.

Int. J. Radiat. Oncol. Biol. Phys., 2017 Feb 17

Stereotactic Radiosurgery and Fractionated Stereotactic Radiation Therapy for the Treatment of Uveal Melanoma.

Br J Ophthalmol, 2013 Jan 19

A comparison between ¹²⁵Iodine brachytherapy and stereotactic radiotherapy in the management of juxtapapillary choroidal melanoma.

JAMA Ophthalmol,

Retrospective evaluation of patients with uveal melanoma treated by stereotactic radiosurgery with and without tumor resection.

International journal of radiation oncology, biology, physics, 2013-05-01

Charged particle radiation therapy for uveal melanoma: a systematic review and meta-analysis.

International journal of radiation oncology, biology, physics, 2017-01-01

Temporal Evolution and Dose-Volume Histogram Predictors of Visual Acuity After Proton Beam Radiation Therapy of Uveal Melanoma.

International journal of radiation oncology, biology, physics, 2015-06-01

Long-term Results of the UCSF-LBNL Randomized Trial: Charged Particle With Helium Ion Versus Iodine-125 Plaque Therapy for Choroidal and Ciliary Body Melanoma.

Int. J. Radiat. Oncol. Biol. Phys.,

Maximizing local tumor control and survival after proton beam radiotherapy of uveal melanoma.

Investigative ophthalmology & visual science, 2006-11

Proton beam irradiation of uveal melanomas: the first 30 years. The Weisenfeld Lecture.

PloS one, 2015

Cost-effectiveness of proton beam therapy for intraocular melanoma.

Br J Ophthalmol, 2013 May 03

Local treatment failure after globe-conserving therapy for choroidal melanoma.

Int J Radiat Oncol Biol Phys, 2016 Jan 28

Practice Patterns Analysis of Ocular Proton Therapy Centers: The International OPTIC Survey.

Saudi J Ophthalmol,

Proton beam radiotherapy of uveal melanoma.

Lancet Oncol., 2014 Aug 07

Trilateral retinoblastoma: a systematic review and meta-analysis.

, 2016 Apr 26

Lymphoid hyperplasia of the orbit and ocular adnexa: A clinical pathologic review.

American journal of clinical oncology, 1992-10

Radiotherapy of lymphoproliferative diseases of the orbit. Surveillance of 65 cases.

Am J Clin Oncol,

Systematic Review and Meta-Analysis on the Use of Photon-based Stereotactic Radiosurgery Versus Fractionated Stereotactic Radiotherapy for the Treatment of Uveal Melanoma.

Archives of ophthalmology (Chicago, Ill. : 1960), 2000-09

Plaque radiotherapy for uveal melanoma: long-term visual outcome in 1106 consecutive patients.

Brachytherapy, 2015

Prescribing to tumor apex in episcleral plaque iodine-125 brachytherapy for medium-sized choroidal melanoma: A single-institutional retrospective review.

Journal of contemporary brachytherapy, 2021 Feb 18

Plaque brachytherapy in iris and iridociliary melanoma: a systematic review of efficacy and complications.

International journal of radiation oncology, biology, physics, 2022 Jan 01

A Story of Hypofractionation and the Table on the Wall.

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