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Pediatric Hematology/Oncology

Fertility Preservation   

Questions discussed in this category

How do you approach fertility preservation in a young child with cancer?
What is the best way to counsel families in regards to their child's risk of infertility and need for fertility preservation?
2 Answers available
Is there a concern for the potential of future congenital malformations in offspring when preservation of eggs and sperm is done AFTER cyclophosphamide treatment given that it is an alkylating agent?
1 Answer available
Do you recommend sperm banking for males prior to undergoing radiation?
Is it necessary to delay the start of radiation therapy for males planning on sperm banking for fertility preservation?
2 Answers available
How long should patients treated with frontline therapy for Hodgkin lymphoma wait before attempting to conceive a child?
Do your recommendations differ between those who receive ABVD and escalated BEACOPP? Do you recommend consultation with fertility specialists for all...
1 Answer available
Can an AYA patient with newly diagnosed AML safely sperm bank after starting cytoreduction with hydroxyurea or cytarabine?
2 Answers available
For pre-menopausal female patients who present with acute leukemia in need of urgent anti-neoplastic therapy, what is your preferred approach in effort to preserve fertility?
Does acute leukemia sub-type affect your decision? 
1 Answer available
Do you offer fertility preservation to patients prior to CAR-T therapy?
Do you limit it to post-pubertal patients? Do you offer it only if they will proceed with bone marrow transplantation after CAR-T?
1 Answer available
What techniques do you use to address fertility preservation in young female patients being treated with chemoradiation therapy for cancer in the pelvis?
How do you prevent early menopause in women? Please comment on freezing of eggs, oophopexy, supine vs prone position, vaginal dialator. 
4 Answers available
When would you consider treating a testicular relapse with definitive radiation in a child with ALL?
1 Answer available


Papers discussed in this category

Cancer, 1994-01-01
Treatment of overt isolated testicular relapse in children on therapy for acute lymphoblastic leukemia. A report from the Childrens Cancer Group.
Med. Pediatr. Oncol.,
Gonadal and sexual function in men treated for childhood cancer.
Arch. Dis. Child.,
Survival and endocrine outcome after testicular relapse in acute lymphoblastic leukaemia.
Pediatric blood & cancer, 2018-05
Isolated late testicular relapse of B-cell acute lymphoblastic leukemia treated with intensive systemic chemotherapy and response-based testicular radiation: A Children's Oncology Group study.
Br. J. Haematol.,
PCR assessment of bone marrow status in 'isolated' extramedullary relapse of childhood B-precursor acute lymphoblastic leukaemia.
Fertil. Steril., 2013 Sep 05
Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: a committee opinion.
Journal of adolescent and young adult oncology, 2020 May 26
Standardizing Risk Assessment for Treatment-Related Gonadal Insufficiency and Infertility in Childhood Adolescent and Young Adult Cancer: The Pediatric Initiative Network Risk Stratification System.
Clin Transl Oncol, 2020 Sep 17
ABVD and BEACOPP regimens' effects on fertility in young males with Hodgkin lymphoma.
J Assist Reprod Genet, 2020 Jun 02
Impact of ABVD chemotherapy on ovarian reserve after fertility preservation in reproductive-aged women with Hodgkin lymphoma.
Lancet Oncol, 2018 Sep 13
Determinants of ovarian function after response-adapted therapy in patients with advanced Hodgkin's lymphoma (RATHL): a secondary analysis of a randomised phase 3 trial.
JCO oncology practice, 2023 Feb 10
Fertility Preservation Practices at Pediatric Oncology Institutions in the United States: A Report From the Children's Oncology Group.

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