Rheumatology

Tocilizumab

Questions discussed in this category

How would you approach a patient with GCA who develops necrotizing fasciitis and then flares because they are off of tocilizumab?

How would you treat? Would you view tocilizumab as an option in the future?

1 Answer available

What is your approach to management of elevated liver enzymes in patients who recently started treatment with tocilizumab?

1 Answer available

How do you manage a patient with giant cell arteritis treated with weekly tocilizumab and low dose glucocorticoid who develops sudden vision loss?

2 Answers available

How long do you continue steroid-sparing agents such as tocilizumab for GCA once the disease is in remission off steroids?

1 Answer available

What is your approach to managing abnormal lipids in a patient on tocilizumab?

1 Answer available

Are you recommending tocilizumab for any COVID-19 patients?

Current guidelines do not support its use, but the EMPACTA trial suggests it may be effective in a subpopulation of patients.

1 Answer available

At what point in GCA management do you typically introduce tocilizumab?

2 Answers available

Is there a role for tocilizumab in treatment of polymyalgia rheumatica in patients who do not have features of giant cell arteritis or rheumatoid arthritis?

1 Answer available

Are subcutaneous RA therapies less effective in obese patients?

1 Answer available

Papers discussed in this category

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Brief Report: A Prospective Open-Label Phase IIa Trial of Tocilizumab in the Treatment of Polymyalgia Rheumatica.

Clin. Rheumatol., 2017 Aug 18

Body mass index and clinical response to intravenous or subcutaneous abatacept in patients with rheumatoid arthritis.

Ann Intern Med, 2020 Sep 22

Risk for Serious Infection With Low-Dose Glucocorticoids in Patients With Rheumatoid Arthritis : A Cohort Study.

N Engl J Med,

Trial of Tocilizumab in Giant-Cell Arteritis.

Lancet, 2016 Mar 04

Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.

N Engl J Med, 2020 Dec 10

Efficacy of Tocilizumab in Patients Hospitalized with Covid-19.

N Engl J Med, 2020 Dec 17

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia.

Arthritis Res Ther, 2021 Mar 22

Vision loss in patients with giant cell arteritis treated with tocilizumab.

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