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Do you add pelvic RT for stage II gr 2 endometrial cancers with multiple high risk features?
Would there be a survival advantage to pelvis RT with deep myometrial invasion, LVSI and ITC?
Answer from: Radiation Oncologist at Community Practice
Yes, I would recommend pelvic RT to a patient with multiple risk factors, especially. It has been shown that stage II patients with substantial LVSI may have a higher risk of pelvic recurrence if treated with brachytherapy alone (Barnes et al., PMID 33485810).The second part regarding survival advan...
Answer from: Radiation Oncologist at Community Practice
Yes. I would offer external beam RT and brachytherapy. It is likely that as with breast cancer, it will take a very long follow up and huge numbers of patients to see a survival advantage. Many of the smaller trials we follow were poorly designed with inaccurate pathology. The NCDB can serve this pu...
I treat according to primary tumor risk factors. ...
I will treat with pelvic XRT.