Do you ever combine voclosporin and belimumab in the treatment of lupus nephritis?
Do you use them sequentially or together?
Answer from: at Academic Institution
The combination of these two therapies has not yet been formally tested. Having said that, the combination has an appealing rationale. Immunologically, modulating T cells and B cells in LN seems likely to be efficacious. Beyond the immunology, there are other reasons that favor this combination. Voc...
I have not used the combination of voclosporin and belimumab, but several have suggested administering voclosporin early on to take advantage of its rapid effects. After the initial period, one could then add Belimumab to take advantage of its long-term benefits.
Patients with LN are typically youn...