Do you ever consider local therapy to oligometastatic hormone-receptor positive breast cancer?  

Surgery or radiation therapy in metastatic breast cancer patient is one of hot topics in care of the patients with stage IV disease, especially since the survival of oligometastatic breast cancer and widely spread metastatic breast cancer is vastly different. For instance, the 5 year survival of oli...

For truly oligometastatic breast cancer, hormone positive or hormone negative, I do consider aggressive local therapy. Obviously, every case is individualized based on the extent of the oligometastasis, response to systemic therapy, and the process of shared decision making. However with low volume ...

I think routine use of SBRT for oligometastatic breast cancer is probably no longer supported given the results of NRG-BR002 (pending final publication). However, for those clinical situations for which local control is a priority, SBRT versus hypofractionated 3DCRT/IMRT/IGRT, could be considered. S...

I think that tumor biology and natural history of a patient's disease are important factors. As noted above, each case should be reviewed in a multi-disciplinary way. When faced with cases such as this, one can favor systemic therapy up front and evaluate the patient's response. If the patient progr...

The question made me wonder local therapy to WHAT? Depending on how I read this, I interpreted it in 2 different ways:1) Do you ever consider definitive local therapy to the breast and all known oligometastatic site(s) (e.g. surgery and/or XRT) in the setting of oligometastatic breast cancer?2) Do y...

We have scaled down significantly after the publication of negative trials including the ECOG study. Sometimes it is driven by the patient and the only advantage not unexpectedly seen in ECOG data was local progression but no impact on QOL.