Do you ever consider using a higher dose of upadacitinib (30 mg daily) for rheumatoid arthritis in patients who fail to respond/partially respond to established dosing of 15 mg daily?   

The FDA-approved dose of upadacitinib (UPA) for the treatment of RA is 15 mg per day. In other diseases, such as psoriatic arthritis (PsA), atopic dermatitis (AD) and ulcerative colitis (UC), higher doses (30mg and 45 mg per day) have been studied and shown to be efficacious and relatively safe when...