Do you follow LFTs in patients on tamoxifen as suggested in the prescribing guidelines?
If so, how often do you check?
Answer from: Medical Oncologist at Academic Institution
I check LFTs about every 6-9 months for patients on tamoxifen. In my practice, most patients with an LFT abnormality will have a G1 AST or ALT abnormality when it is discovered. Therefore, this seems to be frequent enough. If LFTs are abnormal, then I hold tamoxifen, and LFTs usually improve or norm...