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Topics:
Dermatology • Surgical Dermatology
Do you give neoadjuvant intralesional 5FU/MTX prior to Mohs for CSCC purely to reduce scar size and improve cosmetic outcome?
I worry about introducing skip lesions and there is fairly limited data.
Answer from: at Academic Institution
No. With Mohs surgery, we know we can get high cure rates and good cosmetic outcomes.
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Answer from: at Community Practice
I have never given intralesional chemotherapy before Mohs. The idea of shrinking the tumor before Mohs is interesting but I would be concerned with the amount of inflammation this could produce. It could make the interpretation of the Mohs slides more difficult.