Do you have a preferred regimen for patients with HER-2 positive metastatic breast cancer who have progressed through THP followed by T-DM1?  

3rd line and beyond for Her-2 disease is a bit of an open playing field, especially compared to our scripted THP and T-DM1 in the 1st and 2nd lines respectively.  Many use capecitabine + lapatinib, or another chemotherapy backbone and revisit trastuzumab (such as navelbine/trastuzumab, or gem/t...