Do you hold CRRT for a period of time before performing a diuretic challenge in a patient with whom you are assessing for the ability to wean off of continuous dialysis?  

You may want to sit down for this answer, I think the diuretic challenge is overrated and if I’m not mistaken, it was really developed to see if a patient may need to start RRT for Aki, not come off it. I would hardly use it on a patient with aki on Crrt for a decision. It isn’t rocket ...

Please check this reference by Uchino et al., PMID 19623048. Urine output is a major determinant of the success of CRRT weaning. Using a diuretic challenge as a "stress" test of the kidney function (Rewa et al., PMID 31035185) might not be a bad idea as you are contemplating weaning off CCRT (eviden...