Do you offer palliative whole liver radiation for patients with diffuse liver metastases?
What dose-fractionation scheme do you utilize? Are there particular groups of patients this would not be a good option for (i.e. histologies of disease, Child-Pugh score)?
Answer from: Radiation Oncologist at Academic Institution
Whole liver radiation is a very good palliative treatment for diffuse hepatic metastases causing pain or severe nausea/vomiting. I treat the whole liver plus a 1 cm margin to 7-8 Gy/1 fraction per the Phase II trial from Princess Margaret Hospital (Soliman et al., PMID 24062394). In this trial of 41...
Comments
Radiation Oncologist at Princess Margaret Hospital at University of Toronto Thanks, Dr. @Dawn Owen for the nice summary o...
Radiation Oncologist at Northside Hospital Atlanta Agree with Drs. @Dawn Owen and @Laura Dawson!
Ano...
Radiation Oncologist at Baylor Scott & White Clinic - Temple Are you holding systemic therapy while treating wh...
Radiation Oncologist at Mayo Clinic, Rochester I do hold systemic therapy, especially cytotoxic c...
Radiation Oncologist at University of Cincinnati Cancer Center @Laura Dawson and @Dawn Owen, would you consider f...
Radiation Oncologist at Cooper University Hospital Thank you for the excellent answer, @Dawn Owen. I ...
Answer from: Radiation Oncologist at Academic Institution
I have also found palliative whole liver (or nearly whole liver) radiation to provide effective palliation for patients with a very extensive liver disease burden and pain due to distension of the liver capsule. I have generally used this only in patients who no longer have any systemic therapy opti...
Comments
Radiation Oncologist at Mayo Clinic, Rochester I agree with Dr. @Harvey J. Mamon with the caveat ...
Radiation Oncologist at Dattoli Cancer Center This is extreme hypofractionation and I suggest ca...
Radiation Oncologist at Cancer Care Centers of Brevard Dr. @Michael J. Dattoli beat me to it. If your goa...
Thanks, Dr. @Dawn Owen for the nice summary o...
Agree with Drs. @Dawn Owen and @Laura Dawson! Ano...
Are you holding systemic therapy while treating wh...
I do hold systemic therapy, especially cytotoxic c...
@Laura Dawson and @Dawn Owen, would you consider f...
Thank you for the excellent answer, @Dawn Owen. I ...