Do you recommend a specific XRT fractionation for young men with prostate cancer?

Given younger men have a longer period to live, are there concerns regarding long term side effects (GI, GU, secondary malignancy) between SBRT vs hypofractionation vs standard fractionation?

Answer from: Radiation Oncologist at Community Practice

I don't think I would use a different curative dose or fields, but I would use protons. Greater longevity, like 40+ years, increases the risk of 2nd malignancy. The integral dose with protons is about two-thirds less than with Xrays, and the secondary malignancy rate reflects that. The risk is only ...

Comments

Radiation Oncologist at Lake Huron Medical Center
Dr. @Christian Hyde - where does that 31% les...

Radiation Oncologist at Karmanos Cancer Institute - McLaren Proton Therapy Center
Thanks Dr. @Simul Parikh. Protons have a 69% lower...

Radiation Oncologist at Lake Huron Medical Center
Thank you for the reference! - 1% of the patients...

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Do you recommend a specific XRT fractionation for young men with prostate cancer?

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