Do you recommend using Oncotype Dx prior to hormonal or cytotoxic neoadjuvant therapy in LN negative, ER positive/Her2 negative breast cancer?  

Both chemotherapy and endocrine therapy pre-operatively have been shown to improve breast conservation rates. This may not be as well appreciated in the case of hormonal therapy - while complete pathological responses are clearly more often seen with chemotherapy, the relative odds of having breast-...