Do you routinely prescribe memantine for patients who will be receiving hippocampal sparing whole brain RT if they are already on donepezil, or is donepezil alone sufficient?  

I typically prescribe memantine along with WBI and H/A. Not sure there ever was a study comparing the WBI component (with HA) with or without memantine. Maybe that study would show that the HA technique is the major benefit and the drug does very little. Lots of patients are on both memantine and ...