Do you typically load DAPT in patients with ICAD?  

If the ICAD lesion is symptomatic and the patient is aspirin-naive, I administer a one-time loading dose of 325 mg of aspirin, followed by 81 mg after that. I do not administer a loading dose of the P2Y12-inhibiting agent (such as clopidogrel, ticagrelor, etc.). I continue DAPT for 3 months then tra...

For a recent stroke or TIA associated with ICAD, I would initiate dual antiplatelet therapy with a loading dose of aspirin, 300 mg followed by 81 mg daily, and clopidogrel, 600 mg loading dose, and then 75 mg daily for 3 weeks. There is no good evidence in favor of long-term dual antiplatelet Rx in ...