Do you use oral etoposide in combination with carboplatin for small cell lung cancer, in light of the national shortage of IV etoposide?
If so, what would be the regimen?
Answer from: Medical Oncologist at Academic Institution
Our preferred treatment for extensive SCLC is a platinum compound + IV etoposide. However with the national shortage, and our preference to "save" IV etoposide for metastatic germ cell tumors, we would use a platinum compound + irinotecan which is equivalent albeit with more G.I. toxicity. Another e...