Does a genetic predisposition to cancer affect your recommendations regarding breast conservation and radiation?
If a patient has a genetic mutation, but not necessarily the classic ones where we avoid radiation (ATM, BRCA, p53, etc.), does this change your treatment practice at all?
Answer from: Radiation Oncologist at Academic Institution
The question posed makes the assumption that radiation should be avoided in ATM, BRCA, and p53, and asks about other genes. I would begin by stating that radiation should not necessarily be avoided in the vast majority of patients with genetic variants or mutations, even those referred to in the que...