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Does rituximab + lenalidomide have a role in advanced follicular lymphoma?
Although bendamustine + rituximab is a standard option for advanced follicular lymphoma when treatment is required, does the regimen rituximab + lenalidomide also have a role? Initial results were quite remarkable while other studies reveal less enthusiastic results (Fowler et al 2014; Leonard et al 2015).
Answer from: Medical Oncologist at Academic Institution
There has been much interest in replacing traditional chemo-immunotherapy (generally R-bendamustine, R-CHOP or R-CVP) with noncytotoxic therapy such as rituximab plus lenalidomide in patients with previously untreated advanced stage follicular lymphoma. Studies in relapsed/refractory patients have s...
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