Does the better prognosis associated with p16+ H&N cancers relate only to patients who are treated with RT +/- chemo?

The good prognosis of HPV-related OPC pts is observed also in surgical series. Surprisingly, series of TORS find no ststistically differences in TORS for early stage HPV(+) or (-) pts (Cohen MA, Weisndtein Gs et al, Head and Neck 2011), and it is possible that surgical resection of HPV(-) cancers gr...

There are 2 separate questions. Regarding the general question of prognosis, it seems that HPV/p16 association is a favorable prognosistic feature regardless of the mode of therapy. This has led to interest in answering questions in the HPV+ve patients such as if trimodality therapy is always necess...