Does your adjuvant radiation approach differ for ependymomas with RELA fusion?

They are known to have worse prognosis. For an adult with supratentorial G2 ependymomas s/p GTR, radiation is generally not indicated. Does this change with RELA? Any modifications to radiation volume or dose?

Answer from: Radiation Oncologist at Academic Institution

Ependymomas (EPN) can occur either in the cord, the posterior fossa (PF), or supratentorially, and are found both in adults and children. At a very high level, the standard management consists of resection followed by radiotherapy. Although various chemotherapy regimens have been used in several set...

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Radiation Oncologist at USC Keck School of Medicine
@Minesh P. Mehta, thank you very much for such a h...

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Does your adjuvant radiation approach differ for ependymomas with RELA fusion?

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