For a breast cancer patient treated with a mastectomy who has clear indications for post-mastectomy radiation therapy, what do you consider to be the longest acceptable delay prior to initiating PMRT following surgery?

The longest I've ever waited is 6 months, and that was in a young patient with T4b N3b M0 disease that progressed on weekly taxol and then experienced a complete pathologic response to FAC. I felt that this patient had a substantial risk of local-regional recurrence and that even if the benefit of r...