For a small focally positive DCIS margin in the setting of invasive disease and negative invasive margins, not undergoing re-excision, what boost dose would you use?
What if positive margin is felt to be from a DCIS skip lesion (initial DCIS margins widely negative but small focus DCIS found in additional tissue with focally positive margin over a span of <1mm)? Would you boost over 10 Gy?
Answer from: Radiation Oncologist at Academic Institution
Yes. I would give a higher boost dose in the setting of a positive margin. In the old days, at 2 Gy per fraction, I would tx positive margins to a total of 66 Gy, and this usually worked out well. Occasionally, the patient would get some telangiectasias long-term. With Canadian hypofraction, I have ...