For LS-SCLC with radiographic CR after chemotherapy, is there a time point beyond which you do not offer radiation if there is a delay in initiation of radiation?  

I don't think we really have any data guiding this scenario. We know that optimal benefit is achieved when definitive RT is given within the first 2 cycles of chemo. However, I don't think that chemo alone is adequate for total eradication of disease. If the patient is within 1-2 mos of completing c...

This is a very interesting scenario, with a number of features that make it particularly unique: both the fact that the patient was treated solely with chemotherapy, that the patient had a complete radiographic response from chemo alone, that they are now an appropriate candidate for radiation when ...

It sounds like another issue is that, with a radiographic CR, there would no longer be a target though? Diagnostic scan probably would have been taken with deep inspiration and might not match reliable to a CT sim scan?