For male patients with invasive ductal carcinoma s/p unilateral mastectomy, subsequently found to have a BRCA mutation, should a prophylactic contralateral mastectomy be performed?  

As is often the case in rare situations, there is no data to guide decisions. While men with breast cancer are more likey to have BRCA mutations, the risk of breast cancer in men with known mutations is substantially lower than in women with the same mutation. We have not routinely offered bilateral...