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Topics:
Pediatric Hematology/Oncology • Internal Medicine • Hemostasis • Hematology • Benign Hematology • Hemophilia
For mild to moderate hemophilia B, do you routinely screen for inhibitors?
Assume the patient has infrequent bleeding events every few years, with use of FIX replacement for acute bleeds only.
Answer from: at Community Practice
Most experts recommend testing for an inhibitor within 6 to 12 months after concentrate therapy, before any major surgery, and if the patient has a poor response to concentrate therapy (lower than the expected level achieved, or shortened half-life). An annual test is also recommended.
WFH Guidelin...
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