For patients receiving outpatient venetoclax/azacitidine who develop profound neutropenia with ANC <200, do you admit for monitoring during the nadir in the absence of fever?

If not, what instructions do you give to patients regarding checking temperature at home/return precautions?

Answer from: at Community Practice

I don't think I would admit these patients. My recommendation would be to monitor temperature daily or feel febrile and let the clinic know if they have any symptoms of localizing infection. The NCCN and IDSA guidelines talk that only neutropenic patients with fever, even amongst those who have the ...

Answer from: Medical Oncologist at Academic Institution

I do not routinely admit my neutropenic patients on outpatient HMA/Ven treatment in the absence of fever or other evidence of active infection. Patients should avoid acetaminophen, if able to, and monitor their temperature. If they develop a fever of 38.0C or higher for one hour or 38.3C or higher a...

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For patients receiving outpatient venetoclax/azacitidine who develop profound neutropenia with ANC <200, do you admit for monitoring during the nadir in the absence of fever?

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