For Siewert 3 locally advanced GEJ adenocarcinoma, when do you offer preop chemoradiation (CROSS regimen) vs periop chemotherapy (MAGIC or FLOT)?
Answer from: Medical Oncologist at Academic Institution
Siewert I/II GEJ adenocarcinomas are treated according to esophageal cancer algorithms, while Siewert III GEJ adenocarcinomas are treated according to gastric cancer algorithms. Consequently, perioperative chemotherapy with FLOT is the standard, evidence-based approach for fit patients with Siewert ...
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Radiation Oncologist at University Hospital Basel The ESOPEC-trial results are also awaited (FLOT vs...
The ESOPEC-trial results are also awaited (FLOT vs...