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Breast Cancer • Medical Oncology
For triple positive metastatic breast cancer, do you sequence or simultaneously use hormonal therapy along with chemotherapy?
How do you approach treating ER/PR positive/HER-2 positive metastatic breast cancer? Do you combine hormonal therapy / chemotherapy and HER-2 directed therapy together or do you sequence?
Answer from: Medical Oncologist at Academic Institution
There is little evidence to support concurrent administration of endocrine therapy with chemotherapy or chemotherapy plus anti-HER2 therapy, in metastatic breast cancer. Sequential use of endocrine therapy after completing a course of chemotherapy/anti-HER2 therapy is a reasonable alternative that m...
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