Given criticism of GOG 88, and in light of various other recent data, would you deliver definitive XRT in place of inguinal lymph node dissection?
Would you deliver definitive RT in place of inguinal lymph node dissection in light of new data (PMID: 29336837)
In the case of high risk but radiographically negative nodes?
In the case of small burden of gross nodal disease?
Answer from: Radiation Oncologist at Community Practice
Despite GOG 88 findings, a number of retrospective studies have suggested that regional prophylactic RT is an effective method of preventing groin recurrences with minimal morbidity when appropriately delivered. (Combined across retrospective series, the incidence of groin recurrence following treat...