How do you adjust Tamoxifen use in HR+ patients with a history of gastric bypass?
Is there any utility in monitoring serum tamoxifen levels?
Answer from: Medical Oncologist at Academic Institution
No. I do not track levels of tamoxifen in patients who have had gastric bypass. Though I acknowledge that there are reports of tamoxifen being less absorbed in patients after gastric bypass (Willis et al., PMID 20099995), the therapeutic window for tamoxifen is very wide and recurrence after weight ...